Leukemia, Whither Goest Thou?

Computers in practice--whither goest we?

Whither art thou, SCN10A, and what art thou doing?

Since its initial cloning in 1992, SCN5A (Nav1.5) has become known as “the” cardiac sodium channel.1 SCN5A encodes a tetrodotoxin (TTX)-resistant channel that is responsible for the inward sodium current (INa), which initiates the cardiac action potential. Its RNA and protein expression dominate the sodium channel landscape in the ventricle, atrium, and specialized conduction system. Mice heter...

Whither goest the right ventricle in obstructive sleep apnea?

5 and control of hemorrhage technically much easier. Those who are unfamiliar with the instrumentation will find themselves lost; those who are overly enthusiastic will find themselves in trouble; and those who lose sight of their priorities will do harm to their patients. Video thoracoscopy rationally practiced by qualified, responsible physicians offers a great deal to our patients. With cont...

Thou shalt not kill.

Section 241(b) and s. 14 of the Criminal Code unjustifiably infringe s. 7 of the Charter and are of no force or effect to the extent that they prohibit physicianassisted death for a competent adult person who (1) clearly consents to the termination of life and (2) has a grievous and irremediable medical condition (including an illness, disease or disability) that causes enduring suffering that ...

Metastasis: Wherefore Arf Thou?

The small GTP-binding protein Arf6 is known to be an important regulator of the actin cytoskeleton and of cell motility associated with metastasis. A recent study identifies yet another role for Arf6 in metastasis - as a regulator of plasma-membrane-derived microvesicle release.